Open AccessEfficient Methodology for Selective Alkylation of Hydrazine Derivatives
Author(s) -
Aleksei Bredihhin,
Ulrich Groth,
Uno Mäeorg
Publication year - 2007
Publication title -
organic letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.94
H-Index - 239
eISSN - 1523-7060
pISSN - 1523-7052
DOI - 10.1021/ol070026w
Subject(s) - alkylation , chemistry , hydrazine (antidepressant) , combinatorial chemistry , scope (computer science) , organic chemistry , catalysis , chromatography , computer science , programming language
Formation and use of a nitrogen dianion for selective hydrazine alkylation is reported. The scope and limitations of a new method were demonstrated. The novel method provides fast and easy access to substituted hydrazines, which are widely used as drugs, pesticides, and precursors for a variety of compounds in organic synthesis. [reaction: see text]
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