6,8-Di-C-glycosyl Flavonoids from Dendrobium huoshanense
Author(s) -
Chia-Chuan Chang,
Angela Fay Ku,
YunYu Tseng,
WenBin Yang,
JimMin Fang,
ChiHuey Wong
Publication year - 2010
Publication title -
journal of natural products
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.976
H-Index - 139
eISSN - 1520-6025
pISSN - 0163-3864
DOI - 10.1021/np900252f
Subject(s) - flavones , chemistry , glucoside , salicylic acid , shikimic acid , glycoside , malic acid , stereochemistry , chromatography , biochemistry , medicine , alternative medicine , pathology , citric acid
Dendrobium huoshanense is a valued herbal plant used in traditional Chinese medicine. Fractionation of the water-soluble part of D. huoshanense by repeated chromatography culminated in the isolation of four new 6,8-di-C-glycosyl flavones (1-4), in addition to seven known compounds, comprising malic acid, dimethyl malate, N-phenylacetamide, isopentyl butyrate, salicylic acid, shikimic acid, and isoschaftoside. By detailed spectroscopic analysis, the structures of 1-4 were determined to have a core of apigenin bearing pentoside (arabinoside or xyloside) and rhamnosyl-hexoside (glucoside or galactoside) substituents.
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