Open AccessDirect Synthesis of Chrysosplenol D
Author(s) -
George A. Kraus,
Sudipta Raha Roy
Publication year - 2008
Publication title -
journal of natural products
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.976
H-Index - 139
eISSN - 1520-6025
pISSN - 0163-3864
DOI - 10.1021/np800423j
Subject(s) - stereochemistry , chemistry , biology
An aldol condensation and an Algar-Flynn-Oyamada oxidative cyclization were key steps in the direct synthesis of chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials.
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