Prenylbicyclogermacrane Diterpenoids from the Formosan Soft Coral Nephthea pacifica | Zendy

Ali A. ElGamal | Zendy; ShangKwei Wang | Zendy; ChangFeng Dai | Zendy; I-Gin Chen | Zendy; ChangYih Duh | Zendy

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Prenylbicyclogermacrane Diterpenoids from the Formosan Soft Coral Nephthea pacifica

Author(s) -

Ali A. ElGamal,

ShangKwei Wang,

ChangFeng Dai,

I-Gin Chen,

ChangYih Duh

Publication year - 2005

Publication title -

journal of natural products

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.976

H-Index - 139

eISSN - 1520-6025

pISSN - 0163-3864

DOI - 10.1021/np040160e

Subject(s) - coral , stereochemistry , cytotoxicity , methylene , pharmacognosy , terpenoid , spectral analysis , chloride , in vitro , diterpene , chemistry , biology , traditional medicine , biological activity , biochemistry , organic chemistry , medicine , ecology , physics , spectroscopy , quantum mechanics

Ten new prenylbicyclogermacrane diterpenoids, pacificins A-J (1-10), were isolated from the methylene chloride solubles of the Formosan soft coral Nephthea pacifica. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.

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