Junceol A, a New Sesquiterpenoid from the Sea Pen Virgularia juncea
Author(s) -
ShihPin Chen,
PingJyun Sung,
ChangYih Duh,
ChangFeng Dai,
JyhHorng Sheu
Publication year - 2001
Publication title -
journal of natural products
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.976
H-Index - 139
eISSN - 1520-6025
pISSN - 0163-3864
DOI - 10.1021/np010192r
Subject(s) - metabolite , stereochemistry , cytotoxicity , diterpene , terpenoid , cancer cell lines , biology , botany , pharmacognosy , tumor cells , terpene , chemistry , biological activity , cancer cell , biochemistry , cancer , genetics , in vitro , cancer research
A new sesquiterpenoid, junceol A(1), as well as two known diterpenoids, sclerophytin A (2) and cladiellisin (3), have been isolated from the sea pen octocoral Virgularia juncea. The structure of metabolite 1 was determined by extensive spectral analysis. Compounds 1-3 have been shown to exhibit cytotoxicity toward P-388 cancer cells.
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