DNA Tunneling Detector Embedded in a Nanopore | Zendy

Aleksandar P. Ivanov | Zendy; Emanuele Instuli | Zendy; Catriona M. McGilvery | Zendy; Geoff Baldwin | Zendy; David W. McComb | Zendy; Tim Albrecht | Zendy; Joshua B. Edel | Zendy

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DNA Tunneling Detector Embedded in a Nanopore

Author(s) -

Aleksandar P. Ivanov,

Emanuele Instuli,

Catriona M. McGilvery,

Geoff Baldwin,

David W. McComb,

Tim Albrecht,

Joshua B. Edel

Publication year - 2010

Publication title -

nano letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.853

H-Index - 488

eISSN - 1530-6992

pISSN - 1530-6984

DOI - 10.1021/nl103873a

Subject(s) - nanopore , quantum tunnelling , nanotechnology , detector , nanopore sequencing , characterization (materials science) , dna , ionic bonding , scanning tunneling spectroscopy , materials science , fabrication , molecule , optoelectronics , dna sequencing , chemistry , ion , physics , optics , medicine , biochemistry , alternative medicine , organic chemistry , pathology

We report on the fabrication and characterization of a DNA nanopore detector with integrated tunneling electrodes. Functional tunneling devices were identified by tunneling spectroscopy in different solvents and then used in proof-of-principle experiments demonstrating, for the first time, concurrent tunneling detection and ionic current detection of DNA molecules in a nanopore platform. This is an important step toward ultrafast DNA sequencing by tunneling.

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