Single Particle X-ray Diffractive Imaging
Author(s) -
Michael J. Bogan,
W. Henry Benner,
Sébastien Boutet,
Urs Rohner,
Matthias Frank,
Anton Barty,
M. Seibert,
Filipe R. N. C. Maia,
Stefano Marchesini,
S. Bajt,
Bruce W. Woods,
Vincent Riot,
Stefan P. HauRiege,
Martin Svenda,
Erik G. Marklund,
Eberhard Spiller,
János Hajdu,
Henry N. Chapman
Publication year - 2007
Publication title -
nano letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.853
H-Index - 488
eISSN - 1530-6992
pISSN - 1530-6984
DOI - 10.1021/nl072728k
Subject(s) - nanoscopic scale , femtosecond , materials science , biomolecule , characterization (materials science) , optics , nanotechnology , particle (ecology) , nanoparticle , phase (matter) , chemistry , physics , laser , organic chemistry , oceanography , geology
In nanotechnology, strategies for the creation and manipulation of nanoparticles in the gas phase are critically important for surface modification and substrate-free characterization. Recent coherent diffractive imaging with intense femtosecond X-ray pulses has verified the capability of single-shot imaging of nanoscale objects at suboptical resolutions beyond the radiation-induced damage threshold. By intercepting electrospray-generated particles with a single 15 femtosecond soft-X-ray pulse, we demonstrate diffractive imaging of a nanoscale specimen in free flight for the first time, an important step toward imaging uncrystallized biomolecules.
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