Carbohydrate-Based Polymers for Immune Modulation | Zendy

Kenneth Lin | Zendy; Andrea M. Kasko | Zendy

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Carbohydrate-Based Polymers for Immune Modulation

Author(s) -

Kenneth Lin,

Andrea M. Kasko

Publication year - 2014

Publication title -

acs macro letters

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 1.966

H-Index - 92

ISSN - 2161-1653

DOI - 10.1021/mz5002417

Subject(s) - polymer , immune system , carbohydrate , immune modulation , modulation (music) , nanotechnology , materials science , palladium , small molecule , chemistry , computational biology , biochemistry , biology , immunology , organic chemistry , physics , acoustics , catalysis

Carbohydrates play prominent roles in immune surveillance and response to infection. Multivalency, molecular weight control, and molecular architecture control are properties that polymer science is well suited to address. Each of these properties has been demonstrated to impact the biological interaction of carbohydrate-bearing chains with their binding partners. This viewpoint highlights synthetic advances and potential applications of carbohydrate-based polymers for immune modulation. It also offers future directions in polymer science necessary for carbohydrate polymers to fulfill their potential as immune modulators.

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