Synthetic Biology for Therapeutic Applications
Author(s) -
Zhanar Abil,
Xiong Xiong,
Huimin Zhao
Publication year - 2014
Publication title -
molecular pharmaceutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 127
eISSN - 1543-8392
pISSN - 1543-8384
DOI - 10.1021/mp500392q
Subject(s) - synthetic biology , infectious disease (medical specialty) , drug discovery , computational biology , systems biology , cancer therapy , biology , disease , cancer , computer science , bioinformatics , medicine , genetics , pathology
Synthetic biology is a relatively new field with the key aim of designing and constructing biological systems with novel functionalities. Today, synthetic biology devices are making their first steps in contributing new solutions to a number of biomedical challenges, such as emerging bacterial antibiotic resistance and cancer therapy. This review discusses some synthetic biology approaches and applications that were recently used in disease mechanism investigation and disease modeling, drug discovery and production, as well as vaccine development and treatment of infectious diseases, cancer, and metabolic disorders.
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