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Single-Chain Semiconducting Polymer Dots
Author(s) -
Fangmao Ye,
Wei Sun,
Yue Zhang,
Changfeng Wu,
Xuanjun Zhang,
Jiangbo Yu,
Yu Rong,
Miqin Zhang,
Daniel T. Chiu
Publication year - 2014
Publication title -
langmuir
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.042
H-Index - 333
eISSN - 1520-5827
pISSN - 0743-7463
DOI - 10.1021/la5038684
Subject(s) - polymer , nanotechnology , cleavage (geology) , förster resonance energy transfer , chain (unit) , materials science , atomic force microscopy , single chain , fluorescence , chemical engineering , chemistry , physics , optics , composite material , engineering , astronomy , fracture (geology) , antibody , immunology , biology
This work describes the preparation and validation of single-chain semiconducting polymer dots (sPdots), which were generated using a method based on surface immobilization, washing, and cleavage. The sPdots have an ultrasmall size of ∼3.0 nm as determined by atomic force microscopy, a size that is consistent with the anticipated diameter calculated from the molecular weight of the single-chain semiconducting polymer. sPdots should find use in biology and medicine as a new class of fluorescent probes. The FRET assay this work presents is a simple and rapid test to ensure methods developed for preparing sPdot indeed produced single-chain Pdots as designed.

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