[70]Fullerenes Assist the Formation of Phospholipid Bicelles at Low Lipid Concentrations | Zendy

Atsushi Ikeda | Zendy; Kazuya Kiguchi | Zendy; Tomohiro Hida | Zendy; Kazuma Yasuhara | Zendy; Kazuyuki Nobusawa | Zendy; Motofusa Akiyama | Zendy; Wataru Shinoda | Zendy

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[70]Fullerenes Assist the Formation of Phospholipid Bicelles at Low Lipid Concentrations

Author(s) -

Atsushi Ikeda,

Kazuya Kiguchi,

Tomohiro Hida,

Kazuma Yasuhara,

Kazuyuki Nobusawa,

Motofusa Akiyama,

Wataru Shinoda

Publication year - 2014

Publication title -

langmuir

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.042

H-Index - 333

eISSN - 1520-5827

pISSN - 0743-7463

DOI - 10.1021/la503732q

Subject(s) - model lipid bilayer , chemistry , phospholipid , lipid bilayer , fullerene , membrane , crystallography , lipid bilayer phase behavior , organic chemistry , biochemistry

The incorporation of neutral [70]fullerenes (C70) led to bicelle formation in a relatively low lipid concentration range from neutral lipid mixtures (DMPC/DHPC). Furthermore, C70 addition resulted in the formation of large bicelles with a radius of ca. 100 nm, in contrast to C70-free bicelles that were formed from anionic lipid mixtures (DMPC/DHPC/DMPG). The stabilization of these bicelles was attributed to C70 incorporation into the membranes.

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