Phase Coexistence in Single-Lipid Membranes Induced by Buffering Agents | Zendy

Merrell A. Johnson | Zendy; Söenke Seifert | Zendy; Horia I. Petrache | Zendy; Ann C. Kimble-Hill | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Phase Coexistence in Single-Lipid Membranes Induced by Buffering Agents

Author(s) -

Merrell A. Johnson,

Söenke Seifert,

Horia I. Petrache,

Ann C. Kimble-Hill

Publication year - 2014

Publication title -

langmuir

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.042

H-Index - 333

eISSN - 1520-5827

pISSN - 0743-7463

DOI - 10.1021/la5018938

Subject(s) - van der waals force , popc , chemistry , membrane , lipid bilayer , chemical physics , phase (matter) , electrostatics , flexural rigidity , thermodynamics , molecule , organic chemistry , biochemistry , physics

Recent literature has shown that buffers affect the interaction between lipid bilayers through a mechanism that involves van der Waals forces, electrostatics, hydration forces and membrane bending rigidity. This letter shows an additional peculiar effect of buffers on the mixed chain 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) lipid bilayers, namely phase coexistence similar to what was reported by Rappolt et al. for alkali chlorides. The data presented suggest that one phase appears to dehydrate below the value in pure water, while the other phase swells as the concentration of buffer is increased. However, since the two phases must be in osmotic equilibrium with one another, this behavior challenges theoretical models of lipid interactions.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research