Investigation of the Growth Mechanism of Iron Oxide Nanoparticles via a Seed-Mediated Method and Its Cytotoxicity Studies | Zendy

Jing Huang | Zendy; Harshala Parab | Zendy; RuShi Liu | Zendy; TsungChing Lai | Zendy; Michael Hsiao | Zendy; ChungHsuan Chen | Zendy; HwoShuenn Sheu | Zendy; JinMing Chen | Zendy; Din Ping Tsai | Zendy; Y. Hwu | Zendy

Open Access

Investigation of the Growth Mechanism of Iron Oxide Nanoparticles via a Seed-Mediated Method and Its Cytotoxicity Studies

Author(s) -

Jing Huang,

Harshala Parab,

RuShi Liu,

TsungChing Lai,

Michael Hsiao,

ChungHsuan Chen,

HwoShuenn Sheu,

JinMing Chen,

Din Ping Tsai,

Y. Hwu

Publication year - 2008

Publication title -

the journal of physical chemistry c

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.401

H-Index - 289

eISSN - 1932-7455

pISSN - 1932-7447

DOI - 10.1021/jp803452j

Subject(s) - nanoparticle , transmission electron microscopy , iron oxide nanoparticles , materials science , ostwald ripening , magnetic nanoparticles , thermogravimetric analysis , iron oxide , squid , chemical engineering , nanotechnology , metallurgy , ecology , engineering , biology

We report here the development of a seed-mediated growth method for the synthesis of iron oxide nanoparticles with tunable size distribution and magnetic properties. We have investigated the size distribution of seed as well as iron oxide nanoparticles during the growth process using transmission electron microscopy (TEM). It has been observed that the distribution of size gradually becomes narrow with time via the intraparticle ripening process and Oswald ripening process. The magnetization measurements were performed using a superconducting quantum interference device (SQUID) from room temperature t o5Kt odetermine the effect of size distribution on the blocking temperature (Tb) and splitting temperature (Tsplitting). The thermogravimetric analyses exhibited the size-dependent weight loss of the magnetic nanoparticles. The in vitro cytotoxicity tests were also performed to determine the cell viability as a function of size and concentration of the magnetic nanoparticles.

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