Chains of Cobalt Doped Magnetosomes Extracted from AMB-1 Magnetotactic Bacteria for Application in Alternative Magnetic Field Cancer Therapy

International audienceWe report themagnetic properties and heating efficiency of cobalt doped chains of magnetosomes extracted frommagnetotactic bacteria for applications in alternativemagnetic field cancer therapy. The changes of the magnetic properties of the chains of magnetosomes observed in the presence of cobalt are characterized by an enhancement of the magnetocrystalline anisotropy from Keff ∼ 12 KJ/m3 in the absence of cobalt up to Keff ∼ 104 KJ/m3 in the presence of cobalt. We show that these changes are only observed for the magnetosomes organized in chains. Furthermore, the SAR of the extracted chains of magnetosomes mixed in solution and exposed to an oscillating magnetic field of field amplitude 80 mT and frequency 183 kHz is shown to increase from∼400W/gFe for the undoped chains ofmagnetosomes up to ∼500 W/gFe for the cobalt doped chains of magnetosomes