Direct Conversion of Aldehydes to Amides, Tetrazoles, and Triazines in Aqueous Media by One-Pot Tandem Reactions | Zendy

JiunJie Shie | Zendy; JimMin Fang | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Direct Conversion of Aldehydes to Amides, Tetrazoles, and Triazines in Aqueous Media by One-Pot Tandem Reactions

Author(s) -

JiunJie Shie,

JimMin Fang

Publication year - 2002

Publication title -

the journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.2

H-Index - 228

eISSN - 1520-6904

pISSN - 0022-3263

DOI - 10.1021/jo026407z

Subject(s) - chemistry , nitrile , tandem , aqueous medium , sodium azide , hydrogen peroxide , iodine , aqueous solution , ammonia , halide , aldehyde , cycloaddition , organic chemistry , filtration (mathematics) , amide , combinatorial chemistry , catalysis , materials science , statistics , mathematics , composite material

A variety of aldehydes reacted with iodine in ammonia water at room temperature to give the nitrile intermediates, which were trapped by addition of hydrogen peroxide, sodium azide, or dicyandiamide to produce their corresponding amides, tetrazoles, and 1,3,5-triazines in modest to high yields. The one-pot tandem reactions were conducted in water media, and the products were obtained simply by extraction or filtration.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research