Open Access2-Amino-4-oxo-5-substituted-pyrrolo[2,3-d]pyrimidines as Nonclassical Antifolate Inhibitors of Thymidylate Synthase
Author(s) -
Aleem Gangjee,
Farahnaz Mavandadi,
Roy L. Kisliuk,
John J. McGuire,
Sherry F. Queener
Publication year - 1997
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/jm960843u
Subject(s) - thymidylate synthase , chemistry , antifolate , enzyme , enzyme inhibitor , biochemistry , antimetabolite , stereochemistry , chemotherapy , medicine , fluorouracil , toxicity , organic chemistry
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