Open Access2,4-Diamino-5-deaza-6-Substituted Pyrido[2,3-d]pyrimidine Antifolates as Potent and Selective Nonclassical Inhibitors of Dihydrofolate Reductases
Author(s) -
A. Gangjee,
Anil Vasudevan,
Sherry Queener,
Roy L. Kisliuk
Publication year - 1996
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/jm960310l
Subject(s) - chemistry , dihydrofolate reductase , pyrimidine , antifolate , stereochemistry , antimetabolite , biochemistry , enzyme , toxicity , organic chemistry