Open AccessAn Adamantyl-Substituted Retinoid-Derived Molecule That Inhibits Cancer Cell Growth and Angiogenesis by Inducing Apoptosis and Binds to Small Heterodimer Partner Nuclear Receptor: Effects of Modifying Its Carboxylate Group on Apoptosis, Proliferation, and Protein-Tyrosine Phosphatase Activity
Author(s) -
Marcia I. Dawson,
Zebin Xia,
Gang Liu,
Mao Ye,
Joseph A. Fontana,
Lulu Farhana,
Bhamik B. Patel,
Sankari Arumugarajah,
M. S. A. Bhuiyan,
Xiao Kun Zhang,
Younghoon Han,
William B. Stallcup,
Jun Ichi Fukushi,
Tomas Mustelin,
Lutz Tautz,
Ying Su,
Danni L. Harris,
Nahid Waleh,
Peter D. Hobbs,
Ling Jong,
Wan Ru Chao,
Leonard J. Schiff,
Brahma P. Sani
Publication year - 2008
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/jm8010492
Subject(s) - chemistry , apoptosis , angiogenesis , nuclear receptor , carboxylate , cell growth , cancer research , retinoid , receptor , stereochemistry , biochemistry , retinoic acid , gene , transcription factor , biology