Open AccessNovel Potent and Selective Bile Acid Derivatives as TGR5 Agonists: Biological Screening, Structure−Activity Relationships, and Molecular Modeling Studies
Author(s) -
Hiroyuki Satō,
Antonio Macchiarulo,
Charles Thomas,
Antimo Gioiello,
Mizuho Une,
Alan F. Hofmann,
Régis Saladin,
Kristina Schoonjans,
Roberto Pellicciari,
Johan Auwerx
Publication year - 2008
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/jm8007135
Subject(s) - chemistry , g protein coupled bile acid receptor , molecular model , bile acid , biological activity , structure–activity relationship , biochemistry , stereochemistry , pharmacology , in vitro , medicine
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