Two-Carbon-Elongated HIV-1 Protease Inhibitors with a Tertiary-Alcohol-Containing Transition-State Mimic
Author(s) -
Xiongyu Wu,
Per Öhrngren,
Jenny K. Ekegren,
Johan Unge,
Torsten Unge,
Hans Wallberg,
Bertil Samuelsson,
Anders Hallberg,
Mats Larhed
Publication year - 2008
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/jm800209a
Subject(s) - chemistry , alcohol , human immunodeficiency virus (hiv) , protease , hiv 1 protease , transition state analog , stereochemistry , enzyme , biochemistry , virology , active site , biology
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