Open AccessEnzyme Adaptation to Inhibitor Binding: A Cryptic Binding Site in Phenylethanolamine N-Methyltransferase
Author(s) -
Christine L. Gee,
Nyssa Drinkwater,
Joel D. A. Tyndall,
Gary L. Grunewald,
Qian Wu,
Michael J. McLeish,
Jennifer Martin
Publication year - 2007
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/jm701273m
Subject(s) - chemistry , phenylethanolamine n methyltransferase , phenylethanolamine , enzyme , binding site , methyltransferase , enzyme inhibitor , biochemistry , stereochemistry , methylation , dna , tyrosine hydroxylase
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