Open AccessIdentification, Synthesis, and Biological Evaluation of 6-[(6R)-2-(4-Fluorophenyl)-6-(hydroxymethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl]-2-(2-methylphenyl)pyridazin-3(2H)-one (AS1940477), a Potent p38 MAP Kinase Inhibitor
Author(s) -
Toru Asano,
Hitoshi Yamazaki,
Chiyoshi Kasahara,
Hirokazu Kubota,
Toru Kontani,
Yu Harayama,
Kazuki Ohno,
Hidekazu Mizuhara,
Masaharu Yokomoto,
Keiji Misumi,
Tomohiko Kinoshita,
Ohta Mitsuaki,
Makoto Takeuchi
Publication year - 2014
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/jm501222p
Subject(s) - chemistry , hydroxymethyl , stereochemistry , identification (biology) , biological activity , combinatorial chemistry , in vitro , biochemistry , botany , biology
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