Open AccessDesign and Synthesis of Dipeptide Nitriles as Reversible and Potent Cathepsin S Inhibitors.
Author(s) -
Yancey D. Ward,
David Thomson,
Leah L. Frye,
Charles L. Cywin,
Tina M. Morwick,
Michel J. Emmanuel,
Renée Zindell,
Daniel W. McNeil,
Younes Bekkali,
Marc Girardot,
Matt Hrapchak,
Molly DeTuri,
K. Crane,
Della White,
Susan Pav,
Yong Wang,
MingHong Hao,
Christine A. Grygon,
Mark E. Labadia,
Dorothy M. Freeman,
W.F. Davidson,
Jerry L. Hopkins,
Maryanne L. Brown,
Denice M. Spero
Publication year - 2003
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/jm030013y
Subject(s) - chemistry , dipeptide , cathepsin s , cathepsin , stereochemistry , enzyme inhibitor , chemical synthesis , carboxamide , combinatorial chemistry , biochemistry , enzyme , in vitro , peptide
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom