2,4-Diaminothieno[2,3-d]pyrimidine Lipophilic Antifolates as Inhibitors of Pneumocystis carinii and Toxoplasma gondii Dihydrofolate Reductase.
Author(s) -
A. Rosowsky,
Andrew T. Papoulis,
Sherry F. Queener
Publication year - 2002
Publication title -
journal of medicinal chemistry
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/jm020059b
Subject(s) - dihydrofolate reductase , pneumocystis carinii , chemistry , toxoplasma gondii , antifolate , pyrimidine , enzyme , enzyme inhibitor , reductase , biochemistry , stereochemistry , antimetabolite , virology , human immunodeficiency virus (hiv) , organic chemistry , biology , toxicity , pneumocystis jirovecii , genetics , antibody
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