Open AccessAllylic Amination of Alkenes with Iminothianthrenes to Afford Alkyl Allylamines
Author(s) -
Qiang Cheng,
Junting Chen,
Song-Yun Lin,
Tobias Ritter
Publication year - 2020
Publication title -
journal of the american chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.115
H-Index - 612
eISSN - 1520-5126
pISSN - 0002-7863
DOI - 10.1021/jacs.0c08248
Subject(s) - allylic rearrangement , amination , chemistry , reactivity (psychology) , alkyl , organic chemistry , medicinal chemistry , catalysis , medicine , alternative medicine , pathology
Allylic C-H amination is currently accomplished with (sulfon)amides or carbamates. Here we show the first allylic amination that can directly afford alkyl allylamines, enabled by the reactivity of thianthrene-based nitrogen sources that can be prepared from primary amines in a single step.
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