Silver-Mediated Fluorination of Functionalized Aryl Stannanes | Zendy

Takeru Furuya | Zendy; Alexandra E. Strom | Zendy; Tobias Ritter | Zendy

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Silver-Mediated Fluorination of Functionalized Aryl Stannanes

Author(s) -

Takeru Furuya,

Alexandra E. Strom,

Tobias Ritter

Publication year - 2009

Publication title -

journal of the american chemical society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.115

H-Index - 612

eISSN - 1520-5126

pISSN - 0002-7863

DOI - 10.1021/ja8086664

Subject(s) - chemistry , aryl , nucleophile , heteroatom , bimetallic strip , substrate (aquarium) , redox , phenols , combinatorial chemistry , organic chemistry , reagent , catalysis , ring (chemistry) , alkyl , oceanography , geology

We report a regiospecific silver-mediated fluorination of aryl stannanes. The presented reaction can afford complex fluoroarenes from readily available phenols in three steps. The operational simplicity and the broad substrate scope of the fluorination should render this reaction a useful tool for the synthesis of milligram to gram quantities of functionalized aryl fluorides. Silver-mediated oxidative transformations of aryl nucleophiles that proceed via bimetallic redox processes are a new avenue to develop carbon-heteroatom bond formations.

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