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Shining Light on the Dark Side of Imaging: Excited State Absorption Enhancement of a Bis-styryl BODIPY Photoacoustic Contrast Agent
Author(s) -
Mathieu Frenette,
Maryam Hatamimoslehabadi,
Stephanie BellingerBuckley,
Samir Laoui,
Jeffrey La,
Seema Bag,
Srivalleesha Mallidi,
Tayyaba Hasan,
Brett E. Bouma,
Chandra S. Yelleswarapu,
Jonathan Rochford
Publication year - 2014
Publication title -
journal of the american chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.115
H-Index - 612
eISSN - 1520-5126
pISSN - 0002-7863
DOI - 10.1021/ja508600x
Subject(s) - chemistry , excited state , photoacoustic spectroscopy , photoacoustic imaging in biomedicine , photochemistry , absorption (acoustics) , contrast (vision) , bodipy , spectroscopy , absorption spectroscopy , fluorescence , optics , atomic physics , physics , quantum mechanics
A first approach toward understanding the targeted design of molecular photoacoustic contrast agents (MPACs) is presented. Optical and photoacoustic Z-scan spectroscopy was used to identify how nonlinear (excited-state) absorption contributes to enhancing the photoacoustic emission of the curcuminBF2 and bis-styryl (MeOPh)2BODIPY dyes relative to Cy3.

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