Chemoselective Reductive Cross-Coupling of 1,5-Diene-3-ols with Alkynes: A Facile Entry to Stereodefined Skipped Trienes | Zendy

Peter S. Diez | Zendy; Glenn C. Micalizio | Zendy

Open Access

Chemoselective Reductive Cross-Coupling of 1,5-Diene-3-ols with Alkynes: A Facile Entry to Stereodefined Skipped Trienes

Author(s) -

Peter S. Diez,

Glenn C. Micalizio

Publication year - 2010

Publication title -

journal of the american chemical society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.115

H-Index - 612

eISSN - 1520-5126

pISSN - 0002-7863

DOI - 10.1021/ja103836h

Subject(s) - chemistry , diene , selectivity , coupling (piping) , convergent synthesis , combinatorial chemistry , coupling reaction , stereochemistry , organic chemistry , catalysis , mechanical engineering , natural rubber , engineering

A convergent synthesis of highly substituted and stereodefined skipped polyenes is described from the reductive cross-coupling of substituted 1,5-diene-3-ols with alkynes. The control of site selectivity in functionalization of the substituted diene is a central feature of this complex fragment union reaction.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research