A Practical Guide to combinatorial Chemistry

1. Introduction: Combinatorial Chemistry Approaches the Next Millenium 2. Using Computational Tools to Analyze Molecular Diversity SOLID-PHASE STRATEGIES 3. Solid Phase Synthesis: Context 4. Synthesis Tools for Solid-Phase Synthesis 5. On-Resin Analysis in Combinatorial Chemistry 6. Deconvolution Tools for Solid-Phase Synthesis SOLUTION-PHASE STRATEGIES 7. Synthesis Tools for Solution-Phase Synthesis 8. Analytical Tools for Solution-Phase Synthesis 9. Deconvolution Tools in Solution-Phase Synthesis EQUIPMENT AND AUTOMATION 10. Equipment for the High Throughput Organic Synthesis of Chemical Libraries 11. Automated Approaches to Reaction Optimization 12. Application of Automated Parallel Synthesis INFORMATION MANAGEMENT AND BIOLOGICAL APPLICATIONS 13. Information Management 14. Screening of Combinatorial Libraries 15. Summary