Discovery and Development of GDC-0994: A Selective and Efficacious Small Molecule Inhibitor of ERK1/2
Author(s) -
Xin Linghu,
Nicholas Wong,
James F. Blake,
John J. Gaudino,
John G. Moffat
Publication year - 2018
Publication title -
acs symposium series
Language(s) - English
Resource type - Book series
eISSN - 1947-5918
pISSN - 0097-6156
DOI - 10.1021/bk-2018-1307.ch001
Subject(s) - mapk/erk pathway , kinase , extracellular signal regulated kinases , signal transduction , small molecule , extracellular , mitogen activated protein kinase , protein kinase a , chemistry , computational biology , microbiology and biotechnology , biochemistry , biology
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