Open AccessSolution NMR Evidence That the HIV-1 Protease Catalytic Aspartyl Groups Have Different Ionization States in the Complex Formed with the Asymmetric Drug KNI-272
Author(s) -
YunXing Wang,
Darón I. Freedberg,
Toshimasa Yamazaki,
Paul T. Wingfield,
Stephen J. Stahl,
Joshua D. Kaufman,
Yoshiaki Kiso,
Dennis A. Torchia
Publication year - 1997
Publication title -
biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.43
H-Index - 253
eISSN - 1520-4995
pISSN - 0006-2960
DOI - 10.1021/bi965013x
Subject(s) - protease , human immunodeficiency virus (hiv) , ionization , drug , catalysis , hiv 1 protease , chemistry , combinatorial chemistry , stereochemistry , computational chemistry , enzyme , biochemistry , medicine , virology , organic chemistry , pharmacology , ion
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom