English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

The bifunctional catalytic efficacy of alumina-supported gold nanoparticles (Au/Al 2 O 3 ) was investigated for the synthesis of a series of 2-amino-3-aryl-imidazopyridines through the chemoselective reduction of the corresponding 2-nitro-3-aryl-imidazo[1,2- a ]pyridines in high isolated yields. This highly efficient protocol was initially applied for the synthesis of 2-nitro-3-aryl imidazo[1,2- a ]pyridines via the reaction between 2-aminopyridine and nitroalkenes catalyzed by the present catalytic system Au/Al 2 O 3 . Moreover, the heterogeneous surface γ-Al 2 O 3 was also found to catalyze this pathway in a comparable manner. However, only Au/Al 2 O 3 was further proved as the appropriate catalytic system for the selective transfer hydrogenation of the synthesized 2-nitro imidazopyridine derivatives into the corresponding 2-amino-3-aryl imidazo[1,2- a ]pyridines using NaBH 4 as a hydrogen-donor molecule. In addition, the one-pot two-step reaction between nitroalkenes and aminopyridines in the presence of Au/Al 2 O 3 -NaBH 4 provided directly the fast and facile synthesis of 2-amino-3-aryl imidazopyridines, highlighting a useful synthetic application of the catalytic protocol.

Alumina-Supported Gold Nanoparticles as a Bifunctional Catalyst for the Synthesis of 2-Amino-3-arylimidazo[1,2-a]pyridines