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Synthetic Minimal Cell: Self-Reproduction of the Boundary Layer
Author(s) -
Marten Exterkate,
Arnold J. M. Driessen
Publication year - 2019
Publication title -
acs omega
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.779
H-Index - 40
ISSN - 2470-1343
DOI - 10.1021/acsomega.8b02955
Subject(s) - context (archaeology) , reproduction , compartment (ship) , boundary (topology) , layer (electronics) , cell division , microbiology and biotechnology , biology , cell , mathematics , materials science , nanotechnology , biochemistry , ecology , mathematical analysis , paleontology , oceanography , geology
A critical aspect in the bottom-up construction of a synthetic minimal cell is to develop an entity that is capable of self-reproduction. A key role in this process is the expansion and division of the boundary layer that surrounds the compartment, a process in which content loss has to be avoided and the barrier function maintained. Here, we describe the latest developments regarding self-reproduction of a boundary layer with a focus on the growth and division of phospholipid-based membranes in the context of a synthetic minimal cell.

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