Open AccessEffect of Substituents in Different Positions of Aminothiazole Hinge-Binding Scaffolds on Inhibitor–CDK2 Association Probed by Interaction Entropy Method
Author(s) -
Jianzhong Chen,
Xingyu Wang,
John Z. H. Zhang,
Tong Zhu
Publication year - 2018
Publication title -
acs omega
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.779
H-Index - 40
ISSN - 2470-1343
DOI - 10.1021/acsomega.8b02354
Subject(s) - moiety , hydrogen bond , chemistry , stereochemistry , aryl , cyclin dependent kinase 2 , binding site , combinatorial chemistry , sulfonamide , docking (animal) , amino acid , alkyl , biochemistry , enzyme , organic chemistry , molecule , protein kinase a , medicine , nursing
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