Open AccessFacile Synthesis of 3-Arylindenes by HMPA-Promoted Direct Arylation of Indenes with Aryl Fluorides
Author(s) -
Xinfei Ji,
Jialu Li,
Mingsheng Wu,
Song Cao
Publication year - 2018
Publication title -
acs omega
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.779
H-Index - 40
ISSN - 2470-1343
DOI - 10.1021/acsomega.8b01542
Subject(s) - lithium diisopropylamide , hexamethylphosphoramide , aryl , chemistry , lithium (medication) , medicinal chemistry , organic chemistry , ion , psychology , alkyl , psychiatry , deprotonation
A rapid and efficient approach to 3-arylated indenes by reactions of indenes with unactivated fluoroarenes with the assistance of lithium diisopropylamide and hexamethylphosphoramide at room temperature was developed.
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