Open AccessChiral Pentacarboxycyclopentadiene-Based Brønsted Acid-Catalyzed Enantioselective Desymmetrization of Meso-Epoxides by 2-Mercaptobenzothiazoles
Author(s) -
Chao Yuan,
Jun Li,
Pingfan Li
Publication year - 2018
Publication title -
acs omega
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.779
H-Index - 40
ISSN - 2470-1343
DOI - 10.1021/acsomega.8b01207
Subject(s) - desymmetrization , enantioselective synthesis , brønsted–lowry acid–base theory , catalysis , amine gas treating , chemistry , ring (chemistry) , organic chemistry , stereochemistry
Enantioselective desymmetrization of meso-epoxides by 2-mercaptobenzothiazoles was realized by using the pentacarboxycyclopentadiene-based chiral Brønsted acid in combination of N -isopropylaniline as amine additive to give up to 90.5:9.5 er of the ring opening products.
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