Eosin Y-Catalyzed Synthesis of 3-Aminoimidazo[1,2-a]Pyridines via the HAT Process under Visible Light through Formation of the C–N Bond
Author(s) -
Himanshu Singh,
Arsala Kamal,
Savita Kumari,
Dhirendra Kumar,
Suresh Kumar Maury,
Vandana Srivastava,
Sundaram Singh
Publication year - 2020
Publication title -
acs omega
Language(s) - English
Resource type - Journals
ISSN - 2470-1343
DOI - 10.1021/acsomega.0c03941
Subject(s) - eosin y , benzylamine , moiety , catalysis , visible spectrum , environmentally friendly , isocyanide , photochemistry , photocatalysis , chemistry , combinatorial chemistry , materials science , organic chemistry , optoelectronics , ecology , biology
A comfortable, environment-friendly, and metal-free approach for synthesizing the biologically important moiety aminoimidazopyridine through the multicomponent reaction of benzylamine, 2-aminopyridine, and t -butyl isocyanide under visible light using eosin Y as a photocatalyst has been developed. Inexpensive, nontoxic, the effortless accessibility of starting materials, and nonparticipation of particular glassware and a photoreactor system are important qualities of the current approach. Strangely, the mild conditions, environment-friendly, and enumerating tolerance of an extensive range of both electron-donating and electron-withdrawing groups are additional features of the approach.
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