Three-Component Reactions of Alkynone o-Methyloximes, Element Selenium, and Boronic Acids Leading to 4-Organoselenylisoxazoles | Zendy

Jian Wu | Zendy; YeFei Yang | Zendy; Xiaobo Huang | Zendy; Wenxia Gao | Zendy; Yunbing Zhou | Zendy; Miaochang Liu | Zendy; Huayue Wu | Zendy

Open Access

Three-Component Reactions of Alkynone o-Methyloximes, Element Selenium, and Boronic Acids Leading to 4-Organoselenylisoxazoles

Author(s) -

Jian Wu,

YeFei Yang,

Xiaobo Huang,

Wenxia Gao,

Yunbing Zhou,

Miaochang Liu,

Huayue Wu

Publication year - 2020

Publication title -

acs omega

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.779

H-Index - 40

ISSN - 2470-1343

DOI - 10.1021/acsomega.0c03254

Subject(s) - selenium , boronic acid , substrate (aquarium) , chemistry , scope (computer science) , component (thermodynamics) , isoxazole , combinatorial chemistry , organic chemistry , computer science , biology , ecology , physics , programming language , thermodynamics

We report an Ag-catalyzed one-pot three-component reaction of alkynone o -methyloxime, element selenium, and boronic acid, providing a facile route to selenated isoxazole product. This protocol features high efficiency, wide substrate scope, and the use of selenium powder as the selenium source.

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