Open AccessCatalyst-Free [3+2] Cycloaddition of Electron-Deficient Alkynes and o-Hydroxyaryl Azomethine Ylides in Water
Author(s) -
Jin Zhu,
Wenbo Su,
Cheng Xiong,
Ruifang Bai,
Qingfa Zhou,
Ming Chen
Publication year - 2020
Publication title -
acs omega
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.779
H-Index - 40
ISSN - 2470-1343
DOI - 10.1021/acsomega.0c01856
Subject(s) - cycloaddition , catalysis , azomethine ylide , chemistry , medicinal chemistry , organic chemistry , 1,3 dipolar cycloaddition
A catalyst-free [3 + 2] cycloaddition reaction of electron-deficient alkynes and o -hydroxyaryl azomethine ylides in water was developed, affording pyrroline derivatives in moderate to high yields (up to 90%).
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom