Graphene-Wrapped Copper Nanoparticles: An Antimicrobial and Biocompatible Nanomaterial with Valuable Properties for Medical Uses | Zendy

Vasileios Vasilopoulos | Zendy; Maria Pitou | Zendy; Ilias Fekas | Zendy; Rigini Papi | Zendy; Andreas Ouranidis | Zendy; E. Pavlidou | Zendy; P. Patsalas | Zendy; Τheodora Choli-Papadopoulou | Zendy

Open Access

Graphene-Wrapped Copper Nanoparticles: An Antimicrobial and Biocompatible Nanomaterial with Valuable Properties for Medical Uses

Author(s) -

Vasileios Vasilopoulos,

Maria Pitou,

Ilias Fekas,

Rigini Papi,

Andreas Ouranidis,

E. Pavlidou,

P. Patsalas,

Τheodora Choli-Papadopoulou

Publication year - 2020

Publication title -

acs omega

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.779

H-Index - 40

ISSN - 2470-1343

DOI - 10.1021/acsomega.0c00834

Subject(s) - graphene , nanotechnology , biocompatibility , nanostructure , materials science , nanomaterials , biocompatible material , nanoparticle , biomolecule , biomedical engineering , medicine , metallurgy

The great demand for antibacterial, biocompatible, and easily manufactured nanostructures has led to the design and development of graphene-wrapped copper nanoparticles (CuNPs) supported on Si wafers. In this study, we investigated the antibacterial properties of graphene/CuNPs nanostructures against Gram-positive and Gram-negative bacteria. Additional experiments regarding graphene/CuNPs nanostructures behavior against mouse fibroblast cell line L929 indicated their biocompatibility and consequently render them as model biomaterials for medical uses. Biofunctionalization of graphene/CuNPs nanostructures with a high-molecular-weight protein (green fluorescent protein), which retains its functionality after a "tight binding" on the nanostructure's surface, opens the way for attaching and other proteins, or biomolecules of great biological interest, to prepare novel biomaterials.

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