Small Molecule Carboxylates Inhibit Metallo-β-lactamases and Resensitize Carbapenem-Resistant Bacteria to Meropenem | Zendy

Kamaleddin H. M. E. Tehrani | Zendy; Nora C. Brüchle | Zendy; Nicola Wade | Zendy; Vida Mashayekhi | Zendy; Diego Pesce | Zendy; Matthijs J. van Haren | Zendy; Nathaniel I. Martin | Zendy

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Small Molecule Carboxylates Inhibit Metallo-β-lactamases and Resensitize Carbapenem-Resistant Bacteria to Meropenem

Author(s) -

Kamaleddin H. M. E. Tehrani,

Nora C. Brüchle,

Nicola Wade,

Vida Mashayekhi,

Diego Pesce,

Matthijs J. van Haren,

Nathaniel I. Martin

Publication year - 2020

Publication title -

acs infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.324

H-Index - 39

ISSN - 2373-8227

DOI - 10.1021/acsinfecdis.9b00459

Subject(s) - meropenem , isothermal titration calorimetry , acinetobacter calcoaceticus , carbapenem , chemistry , enzyme , dissociation constant , microbiology and biotechnology , acinetobacter baumannii , biochemistry , stereochemistry , minimum inhibitory concentration , ertapenem , enzyme kinetics , bacteria , acinetobacter , biology , in vitro , active site , antibiotics , antibiotic resistance , pseudomonas aeruginosa , genetics , receptor

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