Setting Our Sights on Infectious Diseases | Zendy

Manu De Rycker | Zendy; David Horn | Zendy; Bree B. Aldridge | Zendy; Richard K. Amewu | Zendy; Clifton E. Barry | Zendy; Frederick S. Buckner | Zendy; Sarah Cook | Zendy; Michael A. J. Ferguson | Zendy; Nathalie Gobeau | Zendy; Jennifer Herrmann | Zendy; Paul L. Herrling | Zendy; William Hope | Zendy; Jennifer Keiser | Zendy; María José Lafuente-Monasterio | Zendy; Paul D. Leeson | Zendy; Didier Leroy | Zendy; Ujjini H. Manjunatha | Zendy; James McCarthy | Zendy; Timothy J. Miles | Zendy; Valerie Mizrahi | Zendy; Olena Moshynets | Zendy; Jacquin C. Niles | Zendy; John P. Overington | Zendy; John C. Pottage | Zendy; Srinivasa P. S. Rao | Zendy; Kevin D. Read | Zendy; Isabela Ribeiro | Zendy; Lynn L. Silver | Zendy; Jen Southern | Zendy; Thomas Spangenberg | Zendy; Shyam Sundar | Zendy; Caitlin Taylor | Zendy; Wes Van Voorhis | Zendy; Nicholas J. White | Zendy; Susan Wyllie | Zendy; Paul G. Wyatt | Zendy; Ian H. Gilbert | Zendy

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Setting Our Sights on Infectious Diseases

Author(s) -

Manu De Rycker,

David Horn,

Bree B. Aldridge,

Richard K. Amewu,

Clifton E. Barry,

Frederick S. Buckner,

Sarah Cook,

Michael A. J. Ferguson,

Nathalie Gobeau,

Jennifer Herrmann,

Paul L. Herrling,

William Hope,

Jennifer Keiser,

María José Lafuente-Monasterio,

Paul D. Leeson,

Didier Leroy,

Ujjini H. Manjunatha,

James McCarthy,

Timothy J. Miles,

Valerie Mizrahi,

Olena Moshynets,

Jacquin C. Niles,

John P. Overington,

John C. Pottage,

Srinivasa P. S. Rao,

Kevin D. Read,

Isabela Ribeiro,

Lynn L. Silver,

Jen Southern,

Thomas Spangenberg,

Shyam Sundar,

Caitlin Taylor,

Wes Van Voorhis,

Nicholas J. White,

Susan Wyllie,

Paul G. Wyatt,

Ian H. Gilbert

Publication year - 2019

Publication title -

acs infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.324

H-Index - 39

ISSN - 2373-8227

DOI - 10.1021/acsinfecdis.9b00371

Subject(s) - drug development , medicine , infectious disease (medical specialty) , translational medicine , translational research , session (web analytics) , disease , intensive care medicine , drug , pharmacology , computer science , pathology , world wide web

In May 2019, the Wellcome Centre for Anti-Infectives Research (CAIR) at the University of Dundee, UK, held an international conference with the aim of discussing some key questions around discovering new medicines for infectious diseases and a particular focus on diseases affecting Low and Middle Income Countries. There is an urgent need for new drugs to treat most infectious diseases. We were keen to see if there were lessons that we could learn across different disease areas and between the preclinical and clinical phases with the aim of exploring how we can improve and speed up the drug discovery, translational, and clinical development processes. We started with an introductory session on the current situation and then worked backward from clinical development to combination therapy, pharmacokinetic/pharmacodynamic (PK/PD) studies, drug discovery pathways, and new starting points and targets. This Viewpoint aims to capture some of the learnings.

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