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Early Returns on Small Molecule Therapeutics for SARS-CoV-2
Author(s) -
Mark Namchuk
Publication year - 2021
Publication title -
acs infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.324
H-Index - 39
ISSN - 2373-8227
DOI - 10.1021/acsinfecdis.0c00874
Subject(s) - repurposing , pandemic , covid-19 , drug repositioning , small molecule , data science , computational biology , medicine , computer science , biology , virology , pharmacology , infectious disease (medical specialty) , disease , drug , ecology , genetics , pathology , outbreak
The COVID-19 pandemic has generated an unprecedented response within the scientific community. Extraordinary efforts have been undertaken to identify potential new therapeutics to treat SARS-CoV-2 infection spanning traditional medicinal chemistry, repurposing, and computational approaches. The breadth of the effort and rapid progression of many small molecules to clinical testing provide an opportunity to determine what chemical and testing approaches have been the most efficient in identifying potential treatments and how this may inform preparation for future pandemics.

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