Nanotechnology in Neuroscience Reveals Membrane Mobility Matters | Zendy

Sandra J. Rosenthal | Zendy

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Nanotechnology in Neuroscience Reveals Membrane Mobility Matters

Author(s) -

Sandra J. Rosenthal

Publication year - 2018

Publication title -

acs chemical neuroscience

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 1.158

H-Index - 69

ISSN - 1948-7193

DOI - 10.1021/acschemneuro.8b00495

Subject(s) - quantum dot , neuropsychopharmacology , nanotechnology , photobleaching , membrane , neuroscience , biophysics , chemistry , physics , materials science , biology , genetics , quantum mechanics , fluorescence

Quantum dots are nanometer-sized semiconductors that have size-tunable, narrow emission bands, high quantum yields, and are resistant to photobleaching. Ligand-conjugated quantum dots enable the real time visualization of membrane proteins and have revealed that membrane diffusion dynamics are intrinsic to protein regulation, are susceptible to the level of membrane cholesterol, and are altered in genetic variants linked to disease, suggesting a mise en place approach to neuropsychopharmacology.

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