Optimizing Epitope Conformational Ensembles Using α-Synuclein Cyclic Peptide “Glycindel” Scaffolds: A Customized Immunogen Method for Generating Oligomer-Selective Antibodies for Parkinson’s Disease
Author(s) -
Shawn C. C. Hsueh,
Adekunle Aina,
Andrei Roman,
Neil R. Cashman,
Xubiao Peng,
Steven S. Plotkin
Publication year - 2022
Publication title -
acs chemical neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.158
H-Index - 69
ISSN - 1948-7193
DOI - 10.1021/acschemneuro.1c00567
Subject(s) - immunogen , epitope , oligomer , antibody , alpha synuclein , parkinson's disease , peptide , cyclic peptide , chemistry , disease , synucleinopathies , computational biology , monoclonal antibody , biophysics , neuroscience , biology , medicine , biochemistry , immunology , pathology , organic chemistry
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