Lung Injury in COVID-19—An Emerging Hypothesis | Zendy

Abdulrahman Alharthy | Zendy; Fahad Faqihi | Zendy; Ziad A. Memish | Zendy; Dimitrios Karakitsos | Zendy

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Lung Injury in COVID-19—An Emerging Hypothesis

Author(s) -

Abdulrahman Alharthy,

Fahad Faqihi,

Ziad A. Memish,

Dimitrios Karakitsos

Publication year - 2020

Publication title -

acs chemical neuroscience

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 1.158

H-Index - 69

ISSN - 1948-7193

DOI - 10.1021/acschemneuro.0c00422

Subject(s) - lung , covid-19 , medicine , pathophysiology , diffuse alveolar damage , parenchyma , pathology , immunology , acute respiratory distress , disease , infectious disease (medical specialty)

Lung injury with COVID-19 may be due to a complex underlying pathophysiology. Cytokine release syndrome appears to be a catalyst of different inflammatory pathways promoting lung parenchymal injury and thromboembolic phenomena ("dual hit" injury). Recently, severe neurological manifestations such as acute disseminated encephalomyelitis, which may be not linked to lung pathology, have been identified in COVID-19, contributing thus further to the versatility of its clinical features.

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