Proposed Intranasal Route for Drug Administration in the Management of Central Nervous System Manifestations of COVID-19 | Zendy

Ruqaiyyah Siddiqui | Zendy; Naveed Ahmed Khan | Zendy

Open Access

Proposed Intranasal Route for Drug Administration in the Management of Central Nervous System Manifestations of COVID-19

Author(s) -

Ruqaiyyah Siddiqui,

Naveed Ahmed Khan

Publication year - 2020

Publication title -

acs chemical neuroscience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.158

H-Index - 69

ISSN - 1948-7193

DOI - 10.1021/acschemneuro.0c00288

Subject(s) - nasal administration , central nervous system , covid-19 , medicine , coronavirus , drug , disease , drug delivery , nervous system , intensive care medicine , pharmacology , virology , infectious disease (medical specialty) , outbreak , psychiatry , chemistry , organic chemistry

There is mounting evidence of the central nervous system manifestations associated with COVID-19, particularly in severe cases. Up to 25% of COVID-19 cases exhibit neurological manifestations associated with COVID-19. In view of the devastating nature of the disease due to severe acute respiratory syndrome coronavirus 2, here we debate intranasal drug delivery, in addition to intravenous delivery, as a therapeutic strategy in the management of COVID-19 cases with central nervous system involvement.

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