A WEE1 Inhibitor Analog of AZD1775 Maintains Synergy with Cisplatin and Demonstrates Reduced Single-Agent Cytotoxicity in Medulloblastoma Cells
Author(s) -
Christopher J. Matheson,
Sujatha Venkataraman,
Vladimir Amani,
Peter S. Harris,
Donald S. Backos,
Andrew M. Donson,
Michael F. Wempe,
Nicholas K. Foreman,
Rajeev Vibhakar,
Philip Reigan
Publication year - 2016
Publication title -
acs chemical biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.899
H-Index - 111
eISSN - 1554-8937
pISSN - 1554-8929
DOI - 10.1021/acschembio.6b00466
Subject(s) - medulloblastoma , cytotoxicity , wee1 , cisplatin , cancer research , chemistry , pharmacology , biology , cell , medicine , chemotherapy , biochemistry , in vitro , cell cycle , cyclin dependent kinase 1
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