Open AccessSite-Selective C–H Halogenation Using Flavin-Dependent Halogenases Identified via Family-Wide Activity Profiling
Author(s) -
Brian F. Fisher,
Harrison M. Snodgrass,
Krysten A. Jones,
Mary C. Andorfer,
Jared C. Lewis
Publication year - 2019
Publication title -
acs central science
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 4.893
H-Index - 76
eISSN - 2374-7951
pISSN - 2374-7943
DOI - 10.1021/acscentsci.9b00835
Subject(s) - biocatalysis , flavin group , directed evolution , halogenation , regioselectivity , combinatorial chemistry , chemistry , profiling (computer programming) , enzyme , active site , substrate specificity , substrate (aquarium) , computational biology , stereochemistry , computer science , biochemistry , catalysis , biology , organic chemistry , gene , ionic liquid , ecology , operating system , mutant
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