Open AccessA General Small-Scale Reactor To Enable Standardization and Acceleration of Photocatalytic Reactions
Author(s) -
Chi “Chip” Le,
Michael K. Wismer,
Zhi-Cai Shi,
Rui Zhang,
Donald V. Conway,
Guoqing Li,
Petr Váchal,
Ian W. Davies,
David W. C. MacMillan
Publication year - 2017
Publication title -
acs central science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.893
H-Index - 76
eISSN - 2374-7951
pISSN - 2374-7943
DOI - 10.1021/acscentsci.7b00159
Subject(s) - photocatalysis , standardization , catalysis , process engineering , scale (ratio) , photon , computer science , acceleration , excitation , nanotechnology , biochemical engineering , environmental science , materials science , chemistry , physics , organic chemistry , engineering , electrical engineering , classical mechanics , quantum mechanics , operating system
Photocatalysis for organic synthesis has experienced an exponential growth in the past 10 years. However, the variety of experimental procedures that have been reported to perform photon-based catalyst excitation has hampered the establishment of general protocols to convert visible light into chemical energy. To address this issue, we have designed an integrated photoreactor for enhanced photon capture and catalyst excitation. Moreover, the evaluation of this new reactor in eight photocatalytic transformations that are widely employed in medicinal chemistry settings has confirmed significant performance advantages of this optimized design while enabling a standardized protocol.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom